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IGF-1 LR3 stands for Insulin-like growth factor long arginine 3 (IGF-1 LR3). This peptide is a modified version of IGF-1 (insulin-like growth factor-1), and it was designed to prolong the half life of IGF-1 in circulation. IGF-1 along has a very short half-life in circulation otherwise.
IGF-1 is 70 amino acids in length, whereas IGF-1 LR-3 is 83 amino acids in length. IGF-1 LR3 has thirteen amino acids added at its N position.
The result of the LR3 addition, is that now the IGF-1 maintains its activity in the body and on various tissues, but with a much more prolonged half-life. This means that the results of the IGF-1 LR3 last a long longer than IGF-1 alone. An added benefit is that IGF-1 LR3 has very little affinity for IGFBPs, or insulin-like growth factor binding proteins. It is suggested that the half life of IGF-1 LR3 is 20-30 hours in vivo.
IGF-1, and IGF-1 LR3 bind to the IGF receptor in tissues such as skeletal muscle, adipose (fat) and other tissues, and as a result, this activity stimulates various growth pathways as well as glucose uptake that is more selective to skeletal muscle tissue than adipose tissue. Compare this to insulin (very similar structure and receptor as IGF-1), which is not selective in its energy storing and growth promoting activity between fat tissue and muscle tissue.
Buy IGF-1 LR3 from ELV Bioscience.
This product is for laboratory use and research purposes only.